Habitat: Incredibly adaptable, black bears occupy a greater range of habitats than any bear in the world. Bear home ranges must include food, water, cover, denning sites and diverse habitat types. Although bears are thought to be a mature forest species, they often use a variety of habitat types.Black bears can be found all along the Appalachian Mountains, in the Piedmont area, as well as sporadically along the coast. They prefer habitat that provides cover, such as a densely wooded mature oak forests or swampy area in the coastal plain, and easily accessible food resources.
Female black bears mature as early as three years old. Breeding occurs from mid-June to mid-July, but in the eastern deciduous forest, mating season can extend into August. Female black bears usually breed every other year and cubs are born from early January to mid-February. The cubs are born very nearly hairless and weigh 6-12 ounces (less than a pound!). Anywhere from 1-4 cubs are born at a time and are raised by their mother for about 1 years. They are able to leave the den with the adult female in the spring and they disperse during their second spring. First-year cub mortality rates are about 20%, primarily due to predation (foxes, coyotes, dogs, bobcats, other bears), abandonment by their mother, or displacement. Adult bears do not have natural predators except humans.When the mother is ready to breed again, she will send her yearlings to fend for themselves during the summer months when food is usually abundant. Always hungry, these yearling bears, particularly the males, will seek easy sources of food. The ability to access human related food sources can spell trouble for these bears.
Black Dragons are one of few breeds in the game with an alternate or \"alt\" form. Alt Black Dragons cannot be found in the cave, but will rarely hatch from bred Black Dragon eggs. Alt Black hatchlings have two variations, the \"sitting\" and \"curled\" poses; both will mature into the same adult forms. There is no known way to increase the likelihood of hatching an alt.
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Interestingly, in the same article Lancaster and colleagues further support the worth of their method by establishing organoids from iPS cells derived from microcephalic patients. In keeping with the neuropathology of microcephaly, iPS cells derived from patients carrying a truncating mutation in the CDK5RAP2 gene  generate mini brains that grow smaller than their wild-type controls. In addition, these mutant brain organoids yield a plethora of early differentiating neurons, in keeping with the notion that, in some forms of microcephaly, a dysregulated timing of cell differentiation causes the proliferating progenitor pool to be prematurely depleted. 59ce067264